| abstract |
The present invention provides a sustained-release preparation containing pioglitazone or a salt thereof as an active ingredient having excellent durability. In a dissolution test using the USP paddle method at a rotation speed of 50 rpm and containing pioglitazone or a salt thereof at pH 2.0 KCl / HCl buffer at 37 ° C., the dissolution rate of pioglitazone was averaged at 2 hours A sustained-release preparation characterized by 25-58% and an average of 60-100% at 4 hours. A sustained-release preparation containing pioglitazone or a salt thereof, a hydroxy polymer, and a gel formation accelerator. [Selection figure] None |