http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014530628-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2014530628-A |
titleOfInvention | Assays to identify compounds that modulate bitterness |
abstract | The present invention is based on the Applicants' discovery as disclosed herein for agonists relating to TAS2R receptors TAS2R1, TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R16, TAS2R44, TAS2R46 and TAS2R60. Assignment of agonists to these receptors allows for assays to identify compounds that modulate bitterness. For example, the present invention provides a method for identifying a compound that suppresses the bitter taste caused by these agonists. The present invention also provides a method for identifying compounds that selectively suppress the bitter taste caused by these agonists. The present invention further provides methods for identifying compounds that mimic the bitter taste attributed to these agonists. The present invention also provides a method for identifying compounds that enhance the bitter taste attributed to these agonists. [Selection figure] None |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016523512-A |
priorityDate | 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 288.