| abstract |
The present invention relates to inhibitors of antithrombin III and their medical use in the treatment or prevention of bleeding. Inhibitors are preferably used in subjects suffering from acquired or hereditary bleeding disorders (eg hemophilia) or in clinical conditions characterized by excessive bleeding (eg surgery, trauma, internal bleeding). The The inhibitor of antithrombin III can be, for example, a peptide, aptamer, antibody or antibody fragment that specifically binds and inhibits antithrombin III. [Selection figure] None |