abstract |
In one aspect, the invention provides a substituted (E) -N ′-(1-phenylethylidene) benzohydrazide analog that is useful as an inhibitor of lysine-specific histone demethylases, such as LSD1. Derivatives and related compounds; synthetic methods for producing said compounds; pharmaceutical compositions comprising said compounds; and methods of using said compounds and compositions for treating disorders associated with dysfunction of LSD1 . This summary is intended as a search tool for search purposes in a particular field and is not intended to limit the invention. |