http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014526259-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate | 2012-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014526259-A |
| titleOfInvention | Proteasome deubiquitination inhibitor screening |
| abstract | A method of screening a compound to determine whether the compound is a highly specific proteasome deubiquitination inhibitor comprising contacting the compound with a 26S proteasome human 19S regulatory particle (19S RP), and Determining whether the compound inhibits the activity of the deubiquitinating (DUB) enzymes UCHL5 and USP14. Inhibition of UCHL5 and USP14 activity indicates that the compound is a highly specific proteasome deubiquitination inhibitor. [Selection] Figure 10 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020506230-A |
| priorityDate | 2011-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 309.