| abstract |
The present invention relates to compositions comprising a GLP-2 protein or variant thereof linked to an extended recombinant polypeptide (XTEN), isolated nucleic acids and vectors encoding the compositions and host cells containing the same, and GLP -2 relates to the production and use of such compositions in the treatment of conditions associated with -2. This XTEN is generally a polypeptide having a non-repeating sequence and an unstructured conformation useful as a fusion partner for the GLP-2 peptide in that the properties of the resulting fusion protein are enhanced. |