| abstract |
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions comprising such inhibitors, in particular pharmaceuticals, and the use of such inhibitors in the treatment and prevention of diseases. In particular, the invention relates to new ROCK inhibitors, compositions comprising such inhibitors, in particular pharmaceuticals, and the use of such inhibitors in the treatment and prevention of diseases. In addition, the present invention relates to a method of treating a number of therapeutic indications including sexual dysfunction, inflammatory diseases and ocular diseases, and the use of said compounds in the manufacture of a medicament applied to said therapeutic indications. [Chemical 1] [Selection figure] None |