http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014524253-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10041 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2012-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014524253-A |
| titleOfInvention | Recombinant adenovirus containing trans-splicing ribozyme and cancer therapeutic gene and use thereof |
| abstract | The present invention relates to a recombinant adenovirus comprising a polynucleotide encoding a trans-splicing ribozyme-HSVtk complex acting on a cancer-specific gene and a cancer therapeutic gene, a pharmaceutical composition for cancer prevention or treatment comprising the recombinant adenovirus as an active ingredient, and It relates to a method of treating cancer comprising the step of administering said recombinant adenovirus or pharmaceutical composition to an individual in need of treatment. The recombinant adenovirus of the present invention not only shows selectivity for cancer cells by a trans-splicing ribozyme acting on a cancer-specific gene, but also shows an improvement in anticancer activity by a cancer therapeutic gene. Can be widely used for treatment. |
| priorityDate | 2011-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 664.