| abstract |
The present invention provides relaxin fusion polypeptide A-L-B, in which the relaxin A chain and relaxin B chain are non-wild type, and the A chain and B chain are connected by a linker peptide. The invention further provides a relaxin fusion polypeptide having an extended half-life. Furthermore, the present invention provides nucleic acid sequences encoding the aforementioned fusion polypeptides, vectors containing them, pharmaceutical compositions and medical uses of the fusion polypeptides. |