abstract |
MN-029 dihydrochloride (MN-029.2HCl, Formula 2) is a potent vascular targeting agent. The present invention focuses on the synthesis and characterization of dihydrochloride MN-029 and its pharmaceutically acceptable formulation. Disclosed are methods of using compounds and formulations thereof for the treatment of diseases that depend on the generation of new vasculature by angiogenesis for disease progression. [Selection] Figure 3 |