abstract |
The present invention relates to a suspension of an effective amount of micronized 2- (2-nitro-4-trifluoromethylbenzoyl) -1,3-cyclohexanedione (Nitshinone); and a citrate buffer at pH 2.5-3.5 The present invention relates to liquid pharmaceutical preparations suitable for oral administration, including liquids. This formulation is useful for the treatment of disorders and diseases where inhibition of 4-hydroxyphenylpyruvate dioxygenase (HPPD) is desirable, such as hereditary tyrosinemia type I. |