abstract |
The present invention relates to a non-peptidic polymer-insulin-rich compound in which a non-peptidic polymer and insulin are covalently bound to form at least two non-peptidic polymer-insulin conjugates bound by cobalt ions. Body, method for producing the multimer, kit for production, pharmaceutical composition for preventing or treating diabetes containing the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to an individual . [Selection] Figure 1 |