abstract |
The present invention relates to improved immunogenic compositions and vaccines, methods for their production and their use in medicine. In particular, the invention relates to an immunogenic composition of unconjugated Streptococcus pneumoniae protein selected from pneumolysin and members of the Polyhistidine Triad family (e.g. PhtD). The product contains an adjuvant containing QS21 and monophosphoryl lipid A (MPL) and is presented in the form of liposomes. [Selection figure] None |