| abstract |
In some embodiments, the present invention provides a cell-reactive compstatin analog and a composition comprising the cell-reactive compstatin analog. In some aspects, the invention further provides methods of using cell-reactive compstatin analogs to inhibit, for example, complement-mediated injury to cells, tissues, or organs. In some embodiments, the present invention provides a composition comprising a long-acting compstatin analog and a long-acting compstatin analog. In some aspects, the present invention further provides methods of inhibiting complement-mediated injury to, for example, cells, tissues or organs, using long acting compstatin analogs. In some aspects, the present invention provides a composition comprising a targeted compstatin analog and a targeted compstatin analog. In some aspects, the present invention further provides methods of using the targeted compstatin analog to inhibit complement-mediated injury to, for example, a cell, tissue or organ. [Selection figure] None |