| abstract |
The present invention includes compounds of formula (I) and tautomers and stereoisomers thereof and the compounds, pharmaceutically acceptable salts of the tautomers and stereoisomers, etc. (the variables shown in the formula are Certain iminothiazine compounds as well as their mono and dioxides are disclosed. The compounds of the present invention can be useful as BACE inhibitors and / or can be useful in the treatment and prevention of various pathologies associated therewith. Also disclosed are pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents) and methods for their preparation and use such as Alzheimer's disease. [Chemical 1] |