| abstract |
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions comprising such inhibitors, in particular pharmaceuticals, and the use of such inhibitors in the treatment and prevention of diseases. In particular, the invention relates to new ROCK inhibitors, compositions comprising such inhibitors, in particular pharmaceuticals, and the use of such inhibitors in the treatment and prevention of diseases. In addition, the present invention relates to therapeutic methods and the use of the above compounds in the manufacture of a medicament for application to a number of therapeutic indicators including sexual dysfunction, inflammatory diseases, eye diseases, and respiratory diseases. [Selection] Figure 1 |