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filingDate 2012-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2014511929-A
titleOfInvention Polysaccharides containing two antithrombin III binding sites, their preparation and their use as antithrombotic agents
abstract The present invention is a sulfated polysaccharide having the general structure of a heparin-constituting polysaccharide and having a molecular weight of less than 8000 daltons, comprising the formula (I): (Wherein R1 represents an OH group when the hexasaccharide of formula (I) is located at the reducing end of the polysaccharide, otherwise R1 represents a bond with another sugar unit of the polysaccharide, and R2 represents the formula When the hexasaccharide of (I) is located at the non-reducing end of the polysaccharide, it represents a hydrogen atom. In this case, the bond between carbon atoms 4 and 5 of the first sugar unit of the hexasaccharide is a double bond. Yes, otherwise R2 represents the linkage of the polysaccharide to another sugar unit, in which case the bond between carbon atoms 4 and 5 of the first sugar unit of the hexasaccharide is a single bond.) Relates to a sulfated polysaccharide comprising two antithrombin III-linked hexasaccharide sequences corresponding to The preparation thereof, its use as an antithrombotic agent, and also its use in a method for analyzing samples of heparin derivatives.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019501263-A
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type http://data.epo.org/linked-data/def/patent/Publication

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