| abstract |
The present invention relates generally to the field of TNF ligand family members. More particularly, the present invention is a polypeptide comprising at least three components A each comprising a TNF homology domain (THD) sequence of a TNF ligand family member or a functional derivative thereof, and <12 amino acids It relates to a polypeptide comprising at least one component B consisting of a VL region and a VH region that are directly linked to each other by a linker sequence L having a length. The invention further relates to nucleic acids encoding such polypeptides, and pharmaceutical compositions thereof. |