| abstract |
Compounds that are fatty acid synthesis modulators are provided. These compounds can be used to treat disorders characterized by dysregulation of fatty acid synthase function by modulating the function and / or the fatty acid synthase pathway. Methods are provided for treating such disorders, including viral infections such as hepatitis C infection, cancer and metabolic disorders. The present disclosure addresses the deficiencies of antiviral and anticancer treatment by providing novel heterocyclic modulators of lipid synthesis with improved antiviral and anticancer activity. |