| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-40 |
| filingDate |
2011-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2014-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2014510019-A |
| titleOfInvention |
Process for the preparation of aromatic thiol derivatives by hydrogenation of disulfides. |
| abstract |
The present application relates to the preparation of thiophenols by reacting the corresponding disulfides with hydrogen in the presence of a heterogeneous transition metal hydrogenation catalyst. If the reaction is carried out in the presence of an acylating agent such as a carboxylic acid anhydride or a carboxylic acid halide, an acylated thiophenol is obtained. The pharmaceutically active compound, 2-methylthiopropionic acid S- [2- [1- (2-ethylbutyl) cyclohexylcarbonylamino] -phenyl] is produced by the method described above. |
| priorityDate |
2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |