| abstract |
The present invention relates generally to the fields of topical medication, cosmetics and toiletries. More specifically, the present invention relates to coolants such as n-propyl (R) -2-[((1fl, 2S, 5R) -2-isopropyl-5-methyl-cyclohexanecarbonyl) -amino] -propionate. It relates to the use of a solvent comprising (R) -1,2-propanediol for the ester (CPS-410). The invention also relates to a coolant and a coolant composition comprising 2-propanediol and a method for its preparation. The invention also relates to the use of such coolant compositions in therapy, for example in the treatment of sensory discomfort, in particular skin sensory discomfort (eg pruritus). The invention also relates to the use of such coolant compositions in cosmetics (eg eye makeup products) and toiletries (eg after shave lotions). [Selection figure] None |