http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014508525-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7095 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014508525-A |
| titleOfInvention | Method for identifying a subset of polynucleotides for in vitro determination of the severity of a patient's host response from an initial set of polynucleotides corresponding to the human genome |
| abstract | To determine in vitro the severity of a host response in a patient who is in an acute infectious and / or acute inflammatory condition in a sample using a measuring device comprising a plurality of different genetic probes that represent essentially the entire human genome A method for identifying a subset of polynucleotides from an initial set of polynucleotides corresponding to a human genome, wherein a subject is assigned a clinically determined phenotype group according to its infection and / or inflammation status. The present invention relates to a method for classifying at least two, statistically comparing changes in gene expression signals between phenotype groups, and selecting gene probes whose gene expression signals are statistically significantly changed between at least two phenotype groups . From there, a master score is determined as a measure of the severity of the host response, and by determining a score that does not exceed a predetermined deviation from the master score, fewer polynucleotides are compared to the initial set. Identified. This score may be used to diagnose, predict or monitor the onset of patients' acute infectious and / or inflammatory conditions, and / or to control treatment progression, and / or to control lesions. [Selection] Figure 4 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017033886-A1 |
| priorityDate | 2011-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 232.