http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014506569-A

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filingDate 2012-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2014506569-A
titleOfInvention Expanded utility of red blood cell-derived microparticles (RMP) for the treatment of bleeding
abstract Erythrocyte membrane-derived microparticles (RMP) are safe, economical and effective hemostatic agents in the treatment of a wide range of bleeding conditions and can therefore be considered general-purpose hemostatic agents. Effective RMP is produced from erythrocytes using a high pressure extrusion membrane shearing process. This RMP can be lyophilized after production and can retain activity even when stored at room temperature. Since RMP can be administered to the original donor (self-treatment), transfusion complications can be avoided or can be administered to blood group compatible recipients. RMP generated from type O, Rh minus red blood cells can be provided to any human regardless of blood type. RMP reduces excessive bleeding due to various bleeding disorders such as trauma, surgery, invasive procedures and either congenital or acquired platelet disorders, and either congenital or acquired clotting disorders Can be administered. Administration of RMP prepared according to the present invention demonstrates the effect of safely reducing bleeding.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020508963-A
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