abstract |
The present invention provides a peptide having the sequence SSKITHRIHWESASLLR * , a novel biomarker, wherein the side chain of the C-terminal arginine indicated by an asterisk usually lacks the NH2-C = NH molecule present in the side chain . Disclosed is the usefulness of this biomarker in the diagnosis of neurological and / or neuropsychiatric disorders (especially autism), and a method for measuring the concentration of this new biomarker and the antibody directed against this new biomarker Is also disclosed. Also provided is a treatment for autism comprising administering to a subject a complement factor I inhibitor. |