abstract |
The present invention provides compositions of various glycosylated structures, eg, human antibodies, that function to achieve a desired rate of serum clearance. The present invention also provides methods for modulating the pharmacokinetics of antibodies, eg, human antibodies, and therapeutic compositions containing such antibodies. These methods rely on various glycosylated structures of antibodies, eg, human antibodies, to achieve the desired rate of serum clearance. |