http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014503198-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2011-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014503198-A |
| titleOfInvention | Novel signal sequences that improve protein expression and secretion of recombinant enzymes and other proteins |
| abstract | Disclosed is a polypeptide signal sequence of a modified fragment of a human immunoglobulin heavy chain binding protein (Bip). Also disclosed are fusion proteins comprising a modified fragment of a human immunoglobulin heavy chain binding protein (Bip) operably linked to a heterologous polypeptide. A promoter operably linked to a first DNA sequence encoding a signal sequence comprising a modified fragment of a human immunoglobulin heavy chain binding protein (Bip), and a heterologous polypeptide fused in-frame to the first DNA sequence Also disclosed is a protein expression vector comprising a second DNA sequence encoding. A method for producing a polypeptide, comprising expressing a fusion protein comprising a polypeptide signal sequence of a modified fragment of a human immunoglobulin heavy chain binding protein (Bip) operably linked to a heterologous polypeptide, and said heterologous poly Further disclosed is a method comprising recovering the peptide. [Selection] Figure 1 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021505135-A |
| priorityDate | 2010-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 246.