| abstract |
The present disclosure relates generally to a composition comprising a cross-linked cation binding polymer comprising a monomer containing a carboxylic acid group and a base, wherein the polymer contains less than about 20,000 ppm of non-hydrogen cations, The base is present in an amount sufficient to provide from about 0.2 equivalents to about 0.95 equivalents of base per equivalent of carboxylic acid group in the polymer. The present disclosure also relates to methods of preparing the compositions and methods of using the compositions to treat various diseases or disorders, including those involving ionic and / or fluid imbalances. |