| abstract |
Provided are a method for treating colitis and other inflammatory bowel diseases (for example, ulcerative colitis, Crohn's disease, irritable bowel syndrome and ischemic colitis) and a therapeutic composition. A composition comprising HIF-1α prolyl hydroxylase inhibition, in particular, a 3-hydroxy-2-pyridone derivative represented by the following compound or a pharmacologically acceptable salt thereof. It is preferable from the viewpoint of solubility that the derivative is provided in the form of a methanesulfonyl salt. [Selection figure] None |