abstract |
PROBLEM TO BE SOLVED: To provide a novel autotaxin inhibitor. The present invention is caused by piperidine and pyrazine derivatives according to formulas (Ia), (Ib) and (II) as autotaxin inhibitors, and increased lysophosphatidic acid levels and / or activation of autotaxin. Relates to the use of such compounds for the treatment and / or prevention of mediated and / or amplified physiological and / or pathophysiological conditions, in particular various cancers. [Selection figure] None |