| abstract |
More specifically, the present invention relates to a liposome composition, and more specifically, ceramides can be non-crystallized and encapsulated in liposomes, so that the storage stability is excellent, and liposomes encapsulating non-crystallized ceramide are transdermal. To provide a material that can sufficiently exert an effect of improving the barrier function from absorption to the inside of the stratum corneum of rough skin. The following components (A) to (D): (A) Ceramides (B) Dextrin fatty acid ester satisfying the following conditions (1) to (3) (1) The degree of substitution of the fatty acid per glucose unit is 1.4 to 1.8 (2) The fatty acid The composition is (a) a linear saturated fatty acid having 12 to 22 carbon atoms and (b) a branched saturated fatty acid having 8 to 22 carbon atoms, and the molar ratio of (a) and (b) is 60:40 to 95: (3) A liposome composition comprising (C) phospholipid (D) cholesterol or phytosterol, wherein the average degree of polymerization of glucose in the dextrin moiety is 3 to 150. [Selection figure] None |