http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014196270-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81ab7ff4bc463bbc54ebcb1b961d36ec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-03 |
| filingDate | 2013-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e9c7bd9bdc2ae7b6c4e75737d8122d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e4dbe248db578a397c4a453b626354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a302f7374a8824c0e9efad151a0632b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bd4c6ff6287a3f7564737b6be8b3ddf |
| publicationDate | 2014-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014196270-A |
| titleOfInvention | Pharmaceutical composition for treating or preventing neurodegenerative diseases comprising mitotane |
| abstract | To develop a pharmaceutical composition that suppresses abnormal accumulation of aggregates of TDP-43 for the treatment and / or prevention of TDP-43 proteinopathy. [Solution] The present invention forms an insoluble aggregate containing TAR DNA binding protein-43 (TDP-43) containing one or more compounds selected from the group consisting of mitotane, derivatives thereof and salts thereof as an active ingredient. A pharmaceutical composition for treating or preventing a neurodegenerative disease is provided. The pharmaceutical composition may be the insoluble aggregate formation inhibitor. The neurodegenerative diseases include frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS), Parkinson's disease, ALS / Parkinson dementia complex, Alzheimer's disease, Lewy body dementia, granulopathy Selected from the group consisting of dementia (Grain's disease), Huntington's disease, Perry syndrome, progressive supranuclear palsy, basal ganglia degeneration, Pick's disease, and familial British dementia. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110511992-A |
| priorityDate | 2013-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 159.