| abstract |
PROBLEM TO BE SOLVED: To provide a trivalent bispecific antibody, a production method thereof, a pharmaceutical composition containing the above-mentioned antibody, and use thereof. The trivalent bispecific antibody of the present invention specifically binds to a first antigen and comprises a full-length antibody comprising two antibody heavy chains and two antibody light chains, and the heavy chain. A VH domain fused to one of the C-terminals, and a VL domain fused to the other C-terminal of the heavy chain, wherein the VH domain and the VL domain are Together, they form an antigen binding site that specifically binds to the second antigen. [Selection] Figure 3 |