| abstract |
An object of the present invention is to overcome or at least alleviate conventional difficulties and provide advantageous properties that do not require frequent administration of an effective drug (eg once a day), while reducing the amount of drug Soluble drugs that achieve blood (plasma) levels as achieved by frequent (more than once daily) administration, such as 11- [4- [2- (2-hydroxyethoxy) ethyl]- A sustained release formulation of 1-piperazinyl] -dibenzo [b, f] [1,4] thiazepine or a pharmaceutically acceptable salt is provided. Hydroxypropyl methylcellulose and 11- [4- [2- (2-hydroxyethoxy) ethyl] -1-piperazinyl] dibenzo- [b, f] [1,4] thiazepine or a pharmaceutically acceptable salt thereof Is solved by a sustained release formulation containing one or more pharmaceutically acceptable excipients. [Selection figure] None |