abstract |
Disclosed is a compound for the modulation of thromboxane A2 or peroxisome proliferator-activated receptor. The present invention relates to compounds containing a 1,3-dioxane moiety, their pharmaceutical compositions and the use of said compounds and compositions for the modulation of thromboxane A2 or peroxisome proliferator activated receptors. . Prodrugs, analogs, and pharmaceutically acceptable salts of the compounds, and pharmaceutical compositions can be used in the treatment and prevention of cancer. The compounds of the present invention have thromboxane A2 inhibitory activity and / or peroxisome proliferator-activated receptor activating activity, and therefore the compounds of the present invention may be useful in therapy as antitumor agents. [Selection figure] None |