| abstract |
PROBLEM TO BE SOLVED: To provide a magnetic particle-containing aqueous dispersion unit capable of producing homogeneous functionalities by easy modification and capable of producing a magnetic particle-containing medicine for diagnosis and treatment highly dispersed in an aqueous solution. The surface of magnetic nanoparticles having a primary particle diameter of 10 to 100 nm is coated in the order of the first layer, the second layer, and the third layer, and the first layer is silicon oxide, and the second layer Is a silane coupling agent, amino acid or polysaccharide having a functional group selected from the group consisting of an amino group, a carboxyl group, a hydroxyl group, an azide, and an alkyne, and the third layer is the surface of the second layer. Functional and amide bonds, ester bonds, complex magnetism that is amino acids, polysaccharides, and imines having functional groups selected from the group consisting of amino groups, carboxyl groups, hydroxyl groups, azides, and alkynes that can be modified by click reaction Fine particle powder. [Selection figure] None |