| abstract |
PROBLEM TO BE SOLVED: To provide an estrogen-related receptor modulator which can be used for the treatment of metabolic diseases such as diabetes, obesity and hyperlipidemia. A compound according to formula (VIII), a pharmaceutically acceptable acid or base addition salt thereof, and uses thereof. These compounds, pharmaceutically acceptable acid or base addition salts thereof, modulate the estrogen-related receptor (ERR), resulting in metabolic diseases such as hyperlipidemia, fatty liver, hyperglycemia, diabetes, It can be used for the preparation of a medicament for treating diseases such as obesity. Substituents of this formula are defined in the specification. [Selection figure] None |