| abstract |
Disclosed herein are compounds and compositions for treating disorders associated with TRPA1. SUMMARY OF THE INVENTION Compounds and compositions for treating disorders associated with TRPA1 are described herein. The present invention provides methods and compositions for treating or preventing conditions such as pain by modulating the activity of TRPA1 channels. The compounds described herein inhibit the function of TRPA1 by inhibiting TRPA1-mediated ion flux or by inhibiting inward current, outward current or both currents mediated by TRPA1. adjust. [Selection] Figure 1 |