| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dee0e2a772cd9bebf59cfd68dfd3c3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-16 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-73 |
| filingDate |
2013-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1b56c1c41bb0a1adebbf20cb36f7a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_001ffda5a2f974feffb890bf1ac69dbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7732622fcb44ddb7130134a4b7ba79d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198828160e4e748a4ed5166116ee5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b80453e86375d1170bd2e0a9c3c95bb |
| publicationDate |
2014-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2014141452-A |
| titleOfInvention |
Tyrosine derivative and method for producing tyrosine derivative |
| abstract |
In addition to tyrosine derivatives useful as melatonin MT 1 receptor antagonists, the present invention introduces an iodo group with good regioselectivity and high yield at the para-position of the phenolic hydroxyl group in the benzene ring of m-tyrosine. And it aims at providing the method of manufacturing a specific m-tyrosine derivative efficiently. A tyrosine derivative according to the present invention is represented by the following formula (I). [Wherein R 1 represents an amino-protecting group, etc .; R 2 represents a carboxy-protecting group, etc .; R 3 represents a hydrogen atom group, etc .; R 4 represents a halogen atom group, etc .; , — (CH 2 ) 1 — [Z (CH 2 ) m ] n —; X represents a leaving group] [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014126071-A1 |
| priorityDate |
2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |