| abstract |
An object of the present invention is to provide a granular pharmaceutical composition that is less likely to adhere to a granulated product during granulation, suppresses caking, and is good as a medicine. (B) One or more waxy substances selected from the group consisting of hydrogenated oil, vegetable or animal oil, higher alcohol, polyethylene glycol, higher fatty acid, glycerin fatty acid ester and sucrose fatty acid ester And (A) clopidogrel sulfate and (C) synthetic aluminum silicate and / or hydrous silicon dioxide are dispersed or dissolved therein, and then the dispersion or solution is spray-granulated, and (A) sulfuric acid A granular pharmaceutical composition formed by forming waxy substance particles having a particle diameter of 50 to 200 μm in which clopidogrel is dispersed. [Selection figure] None |