abstract |
The present invention provides a peptide composition that can be used in a preparation that stimulates the production of cell matrix (ECM) protein in the skin to cure damaged skin or maintain healthy skin. A tetrapeptide that stimulates the production of collagen in human skin, wherein the tetrapeptide is PEKP, PKGP, PGQP, PGTP, PGNP. However, P (proline), E (glutamic acid), K (lysine), G (glycine), Q (glutamine), T (threonine), and N (asparagine) are shown. The tetrapeptide is a free acid or amidated at the carboxy terminus. [Selection] Figure 1 |