abstract |
Disclosed is a polypeptide comprising a specific amino acid sequence for the treatment of a medical condition associated with ischemia, and a polynucleotide encoding the polypeptide. A nucleic acid sequence encoding a polypeptide having an amino acid sequence of HIF-1α consisting of subunit α in hypoxia-inducible factor 1 (HIF-1) which is a heterodimeric transcription factor consisting of two subunits. An isolated polynucleotide comprising [Selection figure] None |