| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 |
| filingDate |
2013-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e0963ba30c97d30257fec34d0bbffe1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c68bf5839d5904105192675225e50cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad534a871a0d50bd358d014d31064c5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad7df9018576088ce9f0ecad794beec1 |
| publicationDate |
2014-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2014114285-A |
| titleOfInvention |
Novel synthesis of 3- (2-bromo-4,5-dimethoxyphenyl) propanenitrile and its application to the synthesis of ivabradine and its addition salts with pharmaceutically acceptable acids |
| abstract |
A process for the synthesis of (3- (2-bromo-4,5-dimethoxyphenyl) propanenitrile and its use in the synthesis of ivabradine and its addition salts with pharmaceutically acceptable acids. Formula (I): A process for synthesizing a compound represented by formula (VIII): Wherein the compound of formula (I) is subjected to the action of a base in the presence of acetonitrile in an organic solvent to produce a compound of formula (I). [Selection figure] None |
| priorityDate |
2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |