abstract |
Disclosed is a therapeutic agent for a disease related to cholinergic activity of the central nervous system (CNS) and / or the peripheral nervous system (PNS), which has a strong α7 nicotinic acetylcholine receptor (α7 nAChR) modulating action. A compound of formula (I) or a pharmaceutically acceptable salt thereof. [A is CR 1D or N, XYZ is N-CO-NR 4A R 5 etc., R 1A , R 1B , R 1C and R 1D are C 1-6 alkyl etc., R 2 is H and the like, R 4A , R 4B , R 5 and R 7 are C 3-10 cycloalkyl and the like, R 6 , R 8 and R 9 are H and the like, R 10 to R 17 are H and the like, n Represents 1 or 2.] [Selection figure] None |