Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a140eb40d1e7437d8b8ea7e32eb9785d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb7ce8745175865c6357f7d5fe7fccf5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate |
2014-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75dbc923cf2ecb24d66d96857c882bbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b905867dc94158e530e2478e8eabc4 |
publicationDate |
2014-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2014111633-A |
titleOfInvention |
Prevention and treatment of cerebral amyloid angiopathy |
abstract |
The present invention relates to cerebral amyloid angiopathy (CAA) by reducing vascular amyloid with degeneration of smooth muscle cells and extracellular matrix in the blood vessel wall and / or hyperplasia / hypertrophy and reducing the incidence of cerebral microhemorrhage. Providing methods by peripheral administration such as intravenous or subcutaneous administration to treat. A pharmaceutical composition comprising an antibody, such as a humanized, human or chimeric antibody that binds within the N-terminus of vascular amyloid beta (Aβ), eg, residues 1-5 of Aβ. [Selection figure] None |
priorityDate |
2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |