| abstract |
A method is provided for inducing an immune response in a non-invasive manner. A non-invasive vaccine delivery system for vertebrate skin comprising an immunologically effective concentration of a recombinant adenovirus encoding a transgene of interest. A delivery system wherein the recombinant adenovirus is locally contacted with the skin of an animal in need of such treatment, which induces a protective immune effect following administration, and a) a pad A non-invasive for vertebrate skin comprising an immunologically effective concentration of a recombinant adenovirus complex encoding at least one transgene of interest; A vaccine delivery system, which is applied to the skin to contact the recombinant adenovirus with the skin of an animal in need of such treatment locally. It induces continue to protective immunity effect to the administration, the provision of the delivery system. [Selection figure] None |