| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9d0c82c6254d5b4bec8c96e45c9db7b |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate |
2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93c862f6421b5cfaf945e7db4a359216
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d4fba61812cd0f14f31d29ab8cb79d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25f37b0f5a105e569d79dbf1edda5575 |
| publicationDate |
2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2014095570-A |
| titleOfInvention |
Use of CD300a gene-deficient mice and CD300a-expressing cell activity regulators related to celiac disease, and pharmaceuticals containing CD300a-expressing cell activity regulators |
| abstract |
[PROBLEMS] To provide a useful tool for pathological analysis of celiac disease and a drug for celiac disease. In a CD300a gene-deficient mouse in which celiac disease is induced by gliadin peptide, the symptoms of celiac disease are exacerbated. Therefore, a CD300a gene-deficient mouse is used for analyzing the pathological condition of celiac disease or a therapeutic drug for the same. Alternatively, it can be used as a model mouse for screening candidate substances that can be active ingredients of preventive drugs. In addition, a medicine containing an agent that enhances the inhibitory signaling of myeloid cells expressing CD300a, which contains a substance that enhances the binding between D300a and phosphatidylserine as an active ingredient, treats celiac disease or Can be used to prevent. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017135277-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3412770-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019107445-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299750-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017135277-A1 |
| priorityDate |
2012-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |