| abstract |
An object of the present invention is to provide an effervescent skin external preparation with improved transdermal absorbability of a water-soluble active ingredient. SOLUTION: The foamable skin external preparation containing a water-soluble active ingredient in the skin external preparation which generates carbon dioxide, in particular, consist of two-part separated from one another, one of the two agents bicarbonate and the other contains an acidic substance which generates foam by reacting with bicarbonate, either or both of the two agents, that is at least water-soluble active ingredient, or made from a material, the At least bicarbonate to an agent, the acidic substance to let react with the bicarbonate resulting carbon dioxide, preferably those obtained by containing a water-soluble active ingredient. [Selection] Figure 1 |