| abstract |
Disclosed is a compound that activates soluble guanylate cyclase, which is associated with disorders associated with low cGMP levels such as hypertension, heart failure, pulmonary hypertension, angina pectoris, diabetes, cardiac dysfunction, thrombosis or atherosclerosis Of compounds suitable for the treatment and prevention of such cardiovascular diseases. A pyrimidinyl ring derivative of the formula (I) or a pharmaceutically acceptable salt thereof. A represents an 8 or 9 membered bicyclic heteroaryl ring system comprising a ring fused to a 5 or 6 membered ring such that the attached rings share two adjacent atoms. [Selection figure] None |