abstract |
Provided is a pharmaceutical preparation for treating mammalian rapamycin target protein (mTOR) kinase-dependent diseases. The invention relates to the use of a compound of formula (I) in the treatment of a mammalian rapamycin target protein (mTOR) kinase dependent disease, the use of the compound in the treatment of the disease in a warm-blooded animal (especially human). Methods, pharmaceutical formulations comprising the above compounds for the treatment of the above diseases and the above compounds for use in the treatment of the above diseases. [Selection figure] None |