Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
filingDate |
2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4e7d9cb369ad4b981c363be952a290b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f602c75378bd515556bf83796536b9e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af98122bb3da579940daf6dc12e60c99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88bd91daa7285b2fb3cb0c2bc8cb4cbe |
publicationDate |
2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2014028854-A |
titleOfInvention |
Dosage form and method of drug administration |
abstract |
[PROBLEMS] To provide a dosage form and method for administering a central nervous system drug in a sustained and constantly increasing rate per unit time to obtain an intended therapeutic effect and at the same time reduce the occurrence of an undesirable effect. Provided. Methylphenidate for providing a substantially increased plasma concentration of methylphenidate or a pharmaceutically acceptable salt thereof during a period between 2.5 hours after administration and 5.5 hours after administration. An oral dosage form comprising a hydrogel matrix containing a plurality of pills that releases a date or a pharmaceutically acceptable salt thereof in a sustained and increasing dosage over time, comprising (i) said substantially The above-mentioned oral preparation, wherein the increasing plasma concentration comprises an increase in plasma concentration in a continuous 1 hour increase during the period, and (ii) the peak plasma concentration is reached at or above 4 hours after administration form. [Selection figure] None |
priorityDate |
1996-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |